Sentence examples for mutant displayed only from inspiring English sources

Whereas A73D resulted in a susceptible-like phenotype (S), the A74D mutant displayed only partial activity (S*).

Interestingly, as opposed to the dramatic attenuation of the Y. pestis nlpD mutant shown in the present study, the Y. enterocolitica nlpD mutant displayed only a limited impairment of virulence [45].

Thus, the M2Y129F mutant displayed only marginal defects on tyrosine phosphorylation when compared to its wild type counterpart (Fig. 1A, upper panel), indicating that this site is not the main target of Fyn.

While the diploid tho2Δ mutant was hypersensitive (>125-fold greater than WT) to DOX, the isogenic haploid tho2Δ mutant displayed only a modest (5-fold greater than WT DOXX sensitivity.

Results of both experiments were consistent with those obtained with Endoglycosidase H. Upon treatment with tunicamycin or PNGase F the size of the wild type HGSNAT and the enzyme containing the polymorphism was reduced by approximately ∼10 kDa whereas the inactive mutant displayed only a minor change in electrophoretic mobility.

Mutation of Ser to alanine markedly decreased the binding of 14-3-3 14-3-3 14-3-351A mutation also reduced the interaction, and the double S251A/S336A mutant displayed only trace binding to 14-3-3.

Unexpectedly, the QacR E90 and E120 mutants displayed only modest effects, no greater than 2.7-fold, on the affinities for the drugs examined (Table 1) indicating clearly that these charged residues are relatively minor contributors to drug-binding affinity.

Surprisingly, cdc13-1 pif1Δ mutants displayed only a modest decrease in ssDNA generation in the TG repeats following telomere uncapping, whereas cdc13-1 exo1Δ mutants generated very little ssDNA.

Compared with the wt RNF4-SIM domain, the single SIM mutants displayed only slightly weaker binding to tetra-SUMO2 with KD values in the low micromolar range.

Strikingly, the non-PtdIns(3) P-binding SGK3(R50A) or SGK3 R90A) mutants displayed only low kinase activity and T-loop and hydrophobic motif phosphorylation, suggesting PtdIns(3) P binding to the PX domain plays a critical role in enabling SGK3 to become phosphorylated at its T-loop and hydrophobic motif and therefore become activated.

In contrast, the other Thumb domain mutant, Y108W-N200CCPM, displayed only a fast fluorescence decrease phase (P1) while a P2 phase could not be distinguished.