Sentence examples for mutant derivative of from inspiring English sources

The U87MG-EGFRKD cells express a mutant derivative of U87MG-EGFRvIII where the kinase activity was inactivated by a point mutation in the ATP-binding site [23].

The Flag-tagged hHR23A(c57), a mutant derivative of hHR23A that contains only the COOH-terminal 57 amino acid residues [43], was used as a negative control.

The mutant derivative of this construct (construct pGL3-Cont-BIM UTR-mut) was generated by inverse PCR with the following primers: BIM inv for 5'-CCTGTAGA GandCTGTTTCCTCAGCCCTG-3' and BIM inv rev 5'-TTGAGTCTCACTGGCACGTGAGTA CAGGG-3'.

For instance, a mutant derivative of LT, named LT R192G), when administered intra-nasally with viral epitopes/antigens was shown to induce mixed Th1 and Th2 cellular immunity, and CD8+ CTL responses [24] [27].

Recently Beltramini et al. reported that an stk1 mutant derivative of S. aureus N315 was more susceptible to cell wall-acting antibiotics and showed morphological changes such as incomplete septa and irregular cell size, whereas an stp1 mutant had increased peptidoglycan (PG, [71]).

TEM-116 is a point mutant derivative of TEM-1, Val84→Ile.

We used transient transfection of human embryonic kidney 293T (HEK293T) cells to analyze the effect of ectopic expression of a TFIIB S65A mutant derivative on the activity of a luciferase reporter plasmid linked to the adenovirus major late (AdML) core promoter under the control of the activator BxGalII.

Mutant derivatives of hGBP included the deletion of the entire GTPase domain, and a D184N point mutant that has been reported to lack the GTPase activity [36].

Mutant derivatives of DsRed have been generated to overcome these problems, these include mCherry [15], mKate [16], mPlum [17], tdKatushka [16], tdTomato [15] and Turbo-635 [16].

Wild-type and mutant derivatives of S. coelicolor J1501 were inoculated into 15 mL YEME medium and the cultures were grown for 2 to 3 d.

EBSLs are sometimes mutant derivatives of TEM/SHV, but they are also mobilized from environmental bacteria (e.g. CTX-M) [20].