Sentence examples for mutant demonstrate that from inspiring English sources

Of note, the results obtained with the C-repeat mutant demonstrate that attenuation in the mixed infection model is not caused by any long deletion in the emm5 gene.

Our transfection experiments with the GFP-W22A cortactin point mutant demonstrate that cortactin binding and activation of the Arp2/3 complex is necessary for pedestal formation, which suggests that cortactin indeed contributes to efficient actin polymerization.

Spectroscopic, pre-steady-state and steady-state kinetic, thermodynamic, theoretical, and structural studies of the mutant demonstrate that formation of an H-bond between His429 and the unbonded electron pair of the Cys436 axial thiolate significantly alters the properties of the enzyme.

MD simulations of the single mutant demonstrate that loop 1 appeared to be less mobile than that of wild-type caspase-3 due to replacement of F128 on β-strand 4. Thus, double mutant F128A/V266H exhibited activity only ∼20-fold lower than that of the F128A single variant.

However, SMX had no effect on nuc-1 mutants, demonstrating that animals maintain a functional folate cycle.

The increase was less pronounced with the Ala mutants, demonstrating that introduction of negative charges at the distinct positions in the UNG2 regulatory domain specifically stimulates the activity of UNG2.

Physiological characterization of each mutant demonstrated that the growth and metabolites accumulation properties of these mutations exhibited significant change upon pathway engineering.

Surprisingly, analyses of the hydA1-1 and hydA2-1 single mutants, as well as the HYDA1 and HYDA2 rescued hydA1-1 hydemonstrated demonsthated that both hydrogenases are able to catalyze H2 production from either fermentative or photosynthetic pathways.

Studies with the NS2A mutant demonstrated that it was unable to produce a larger form of NS1 (Nsuggestingesthat thet the mutation had been selected to eliminate a ribosomal frame-shift "slippage site" in NS2A.

Non-catalytic Cys286 was identified as the only site of modification, but further mutagenesis studies using the C286Q mutant demonstrated that this site was not responsible for inhibition of EhTrxR by Auranofin.

Enzymatic analysis using bacterial extracts from the WT and the tpx mutant demonstrated that the mutant contains reduced peroxidase activity.