Sentence examples for mutant data available from inspiring English sources
In order to determine whether the genes identified as unbound (or bound below the detection limit) by MSL are in fact independent of the MSL-complex, we turned to MSL-complex component RNAi knock-down and mutant data available from S2 cells and male larvae, respectively.
Although no mutant data are available for C. cinereus ctp1, BLAST searches identify a putative ortholog containing a CtIP C-terminus domain (data not shown) (Marchler-Bauer et al. 2013).
The large amount of mutant phenotype data available together with several gaps in knowledge of network details call for computational modeling as a tool for understanding the complex regulation at a systems level.
For comparison, a plot of all presently available Kv4.3 S4 mutant data is illustrated in Figure 4.
We show here that the BMP-receptor interaction meets the conditions for a Schnakenberg-type Turing pattern, and that the resulting model reproduces available wildtype and mutant data on the expression patterns of BMP, its receptor, and Fgfs in the apical ectodermal ridge (AER) when solved on a realistic 2D domain that we extracted from limb bud images of E11.5 mouse embryos.
> -wrap-foot> For many genes, there are now data available on associated mutant phenotypes (Tweedie et al. 2009) and time series expression profiles (Graveley et al. 2011).
The notion that oxidative damage is, at most, mildly increased in mitochondrial SOD mutants is also consistent with the limited biomarker data available in the literature.
The transcriptional response to HS was measured in Hsf4 mutant 3rd instar larvae using the same approach described above (data available in GEO under GSE22332).
Mutants with higher aggregation propensities compose a group of mutations in which the clinical data available is more abundant.
On the basis of structural data available for PstP and alignment with the residues important for Human PP2Cα activity [18], PstPc mutants were generated using site-directed mutagenesis.
