Sentence examples for mutant could serve from inspiring English sources

These findings support that an N-terminus-truncated mutant could serve as a specific genetically encoded inhibitor for L-channels.

These results from application of the myd88 mutant in a zebrafish model for tuberculosis illustrate how this mutant could serve as a valuable tool for studying innate immune responses in many other zebrafish models that have been developed in recent years for human infectious diseases, inflammatory disorders and cancer.

Given the central role of thin filament regulation on myocyte performance and the realization that both thin and thick filament CM mutant proteins directly alter myofilament activation [39], [42] [44], we reasoned that representative thin filament CM mutants could serve as surrogates for the breadth of thin and thick filament CM mutant alleles.

Knockout mutants could serve as ultimate proof for ZmTSA being essential.

In this speculative case, the use of TRAIL death receptor-specific TRAIL mutants could serve as an option to reduce potential side effects related to activation of the TRAIL death receptor type not relevant for apoptosis induction in the targeted tumor type.

Therefore, this monomeric mutant protein could serve as a drug target for a high throughput inhibitor screening assays, since its binding pocket is unoccupied in solution and potentially more accessible to small molecule ligands.

These mutant repositories could serve as a valuable resource for mining of novel functional alleles regulating qualitative and quantitative traits for genetic improvement in rice.

As expected, all of the selected mutants endowed the host cells with elevated mutation rates, ranging from 7.7 folds (dnaQ KR4-1) to 2839 folds (dnaQ BR1), which indicated the genetically modified dnaQ mutants enriched in GREACE could serve as endogenous mutators to accelerate evolution.

Mutant proteins secreted into the serum could serve as useful biomarkers for the early detection of MSI-High tumours, particularly in the HNPCC affected population.

The high frequency of arteriovenous crossings in Nrp1 cytoΔ /Δ mutants raises the possibility that these mice could serve as an animal model to elucidate the poorly understood aetiology of BRVO.

Having established that NMD-resistant transcripts can give rise to expressed MSI-derived mutant proteins, we sought to identify additional cMS-containing genes likely to generate expressed mutant proteins in MSI-High colon cancers that could serve as therapeutic targets.