Sentence examples for mutant could contribute from inspiring English sources

Thus, downregulation of these genes in the phoP mutant could contribute to attenuation.

In this context, downregulation of the cysH gene in the phoP mutant could contribute to the attenuated phenotype and the protection against disease displayed by this strain.

Conversely, the Beijing strain associated with epidemic spread and enhanced virulence has been shown to constitutively express the DosR regulon [48], which suggests a possible role for the DosR regulon in virulence and consequently, downregulation of DosR in the phoP mutant could contribute to the attenuated phenotype of this strain.

However, it is possible that upregulation of unannotated non-coding transcripts mapped upstream of FLO1 in the cyc8 mutant could contribute to the upstream histone loss shown [68].

Based on our previous study, we hypothesized that the difference in fungal cell surface structure between the wild type and itr1aΔ itr3cΔ mutant could contribute to the differential host response in the infected mouse brains.

It is tempting to speculate that reduced glutamate uptake by astrocytes in Clock/Clock mutants could contribute to their enhanced locomotor and physiological responses to cocaine, behaviors and neuroplastic changes in which a glutamatergic component has been demonstrated [31].

The ddm1 mutation introduces profound changes in chromatin state [ 41]; chromatin changes of the type observed in ddm1 mutants, could contribute to apparent genome size differences but are unlikely to be the main determinant of the Loh-0 to Col-0 difference.

Chimeric embryos bearing both wild-type (white) and varying amounts of mutant cells (blue) were examined to determine whether Rx mutant cells could contribute to eye structures in a wild type environment.

Nevertheless, it is possible that both a reduction in mRNA expression and nuclear entry of the mutant protein could contribute to the delayed phenotype in mice with longer repeats.

This raises the possibility that the shorter endogenous period of the mutant mice could contribute to the deficits in recall, because of a greater mismatch with the 24 h period of the LD cycle.

The mutant forms of p53 in HC11 cells are thought to contribute to their immortalisation [ 95], but it is not known if, under certain conditions, mutant p53 could contribute to the sensitisation of cells to starvation-induced apoptosis as does wild-type p53 [ 96].