Sentence examples for mutant copy is from inspiring English sources

The transposon ISRpe1, originally identified in R. peacockii, [10] is also found twice in the R. massiliae genome along with a gene fragment (E = 0.0; RMand538 and RMA_0748) and a frameshifted mutant copy is found on the R. felis plasmid (E = 4e−154; RF_p4e−154

Furthermore, OCG mutations are usually dominant so that one mutant copy is enough to start switching on a cellular activity.

The risk for the carriers, who have a single mutant copy, is almost ten times that of normal age-matched controls.

When one mutant copy was present for both genes simultaneously in the same neurons (transheterozygous condition; DAAM−/+ Sop2−/+), this combined reduction of both proteins became rate-limiting, and neurons displayed significantly reduced filopodia numbers (75%; Fig. 3A).

This implies that once a critical threshold of mutant DNA copies is reached, normal mitochondrial function may be altered.

nrdHIEF however, is poorly expressed and can not complement an nrdAB conditional mutant unless a second nrdHIEF copy is provided, either as a merodiploid or in a plasmid-based copy [16].

Complementation of gene deletion mutants with the wild-type gene copy is an essential control to prove the function of a gene of interest.

In recessively inherited disorders, two copies of a mutant gene are necessary for the disorder to manifest; if only one copy is inherited, the offspring is not affected, but the trait may continue to be passed on to future offspring.

Also if we assume that a random copy is transferred in a conjugational event, the probability of getting transferred will be higher for a copy-up mutant.

If 10 mutant template copies are needed for accurate percentage variant calling by NGS, then one would expect that FFPE specimens with 1.2% QFI would require a minimum of 27.8% (10/36) mutant templates to be reliably quantified.

A point estimate of the average number of mutant JAK2 copies was obtained as the value of λ that maximises the likelihood of this distribution, given the observed number (y) of mutant JAK2 copies in each experimental replicate (see formula above).