Exact(5)
In this study, we explored the impact of this novel mutation on the aggregation, cellular and biophysical properties of α-Syn, in an attempt to unravel how this mutant contributes to PD/MSA.
Upregulation of string in the miR-965 mutant contributes to the defects in histoblast proliferation.
However, our structural and functional assays suggest that Arg109, the second residue of the MBP-Norrin K54E/R109E mutant, contributes to GAG binding rather than Lrp5/6 binding.
We hypothesize that the residual ESAT-6 secretion of the FAM58 mutant contributes to the difference in infection level (20% versus 3.5%; compare Fig. 2D with Fig. 1E).
If the altered cell wall organization observed in the vti13 mutant contributes to its growth phenotype in root hairs, lowering the pH in the growth medium may help relieve aberrant interactions between wall polymers and result in root hairs whose length is more similar to those of wild-type seedlings.
Similar(55)
It is likely that the severely defective TRbeta mutant contributed to the extreme RTH phenotype and resistance in our patient.
The Δpnc1 mutant contributed to 69.9% decrease in the intracellular NAD+ concentration in stationary phase (29), while kynurenine and 3- OH -kynurenine in the cell, which are precursors of NAD+ from kynurenine pathway, were absent in the Δbna6 mutant (3- OH -kynurenine
This clearly indicates that increased expression levels of NCED3 and NCED5 in the wrky33 mutant contribute to susceptibility toward B. cinerea 2100, and that a key function of WRKY33 in host immunity towards this pathogen is to repress ABA biosynthesis.
It was shown that the overexpression of TGase zymogen gene in the mutants contributes to the increase in TGase production.
It is also possible that defects in phragmoplast formation in these mutants contributes to, or is associated with, the observed defective PIN protein localization.
Currently, we do not know whether the massive reduction of microvasculature in the WAT of Nscl-2 mutants contributes to the phenotype.
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