Sentence examples for mutant composed of from inspiring English sources

To further reduce membrane binding, we designed a Lipid-5A mutant consisting of Lipid-4A and K159A, and a Lipid-7A mutant composed of all seven basic wing residues converted to alanine.

The dhfr/dhps quintuple mutant, composed of dhfr 51I, 59R, and 108N and dhps 437G and 540Q mutations, was found in 95% of episodes from children who continued co-trimoxazole and 91% of episodes from children who discontinued co-trimoxazole (relative risk 1.05 (0.98 to 1.13), P=0.17).

Moreover, recent studies revealed that deletion of the receptor-binding domain of BoNT/A alone (or together with the LC) disrupted low-pH sensing activity and the mutant (composed of the translocation domain and the LC or the translocation domain alone) was constitutively active for channel formation, even at neutral pH.

A monomer of the PDE9Q453E mutant is composed of 16 helices (Fig. 2A) that are folded into a similar topology as PDE9 and other PDE families [17].

Morphological examination showed that E12.5 mutant livers, composed of four lobes, were extremely pale and severely reduced in size as compared to normal livers (Fig. 2E).

Each subunit of wild-type NdCld and its mutants is composed of two topologically equivalent ferredoxin-like domains, as was described in detail by Kostan et al. The overall structure of the subunits of the mutants does not change compared to the wild-type protein, with r.m.s.d.

As the mutant phenotype is composed of all the mutant sequences except the master sequence, back mutation can be neglected as a first approximation.

The total mutant population is composed of a sum of J i.i.d quantities distributed as Q, and J itself is Poisson.

Moreover, recent work has shown that IDH-mutant gliomas are composed of two predominant subtypes, those with and those without 1p/19q chromosomal codeletion (IDHmut-codel and IDHmut-noncodel), with the IDHmut-noncodel subclass not only harboring the vast majority of ATRX-mutant tumors, but also exhibiting uniformly low-level ATRX expression2.

The mutant loxP system, which is composed of two different mutant loxP sites (loxP_RE and loxP_LE), was first utilized for genetic manipulation of tobacco [ 4].

PTEN mutant cells overgrow in a cell-autonomous manner as the enlarged ommatidia were exclusively composed of mutant cells.