Sentence examples for mutant cells reported from inspiring English sources

This heat-induced circular structure was not found either in wsc1Δ or bck1Δ mutants that are defective in the CWI signaling pathway, nor in chs1Δ, chs3Δ and bni1Δ mutant cells, reported to be deficient in the proper budding process.

Similarly, defects in rDNA silencing and in the association of Net1 and Sir2 were observed for H3K79A mutant cells, as previously reported [ 23].

Even, YAP1 mutant cells that have been reported to be very light-sensitive [ 38], are still able to grow under these conditions, although slower than wild type cells (Additional file 1: Figure S1B).

These mutant cells are different from earlier reported mutant cells as the eEF-2 of these cells are sensitive to toxin-induced ADP-ribosylation while the cells show reduced sensitivity.

As previously reported, atg1 mutant cells exhibited decreased viability after two days of starvation, and almost completely atg1Δ cells died after five days (3.0% of survival cells).

Yet, the limited upregulation of katB was surprising, as KatB is supposed to be the major catalase/peroxidase in B. cenocepacia and hypersensitivity of planktonic B. cenocepacia MDL2 (katB mutant) cells to H2O2 has been reported [ 12].

It is noteworthy that the NBS1 recruitment defects we observed in MDC1SDTDΔ mutant cells are similar to those reported for cells containing NBS1 with mutations in its FHA domain (Lukas et al, 2004), suggesting that the FHA domain of NBS1 binds to MDC1.

These results further suggest that in Huh7 cells mutant p53 (Y220C) reported to be transcriptionally inactive [ 25], may indeed be active but its transcription activity may be strongly suppressed by FBP1.

Hence, as in CML [ 46- 48] and FLT-3 mutant [ 49] AML cells, Bim is also emerging as a central cell death driver in JAK2V617F mutant cells ([ 21], and this report).

Defects in mitosis have been reported previously for other LMNA mutant cells [6].

Ultraviolet (UV) rays damage a key gene in skin cells involved in fighting off tumors, and at the same time appear to help these dangerous mutant cells survive sun exposure, says a report in the 26 November issue of the Proceedings of the National Academy of Sciences.