Sentence examples for mutant cells relative from inspiring English sources

However, a growth advantage was not observed in ctf7-203 elg1 rad24 triple mutant cells, relative to ctf7-203 elg1 double mutant cells (data not shown).

Combination targeting of these functions caused improved killing of KRAS mutant cells relative to wild-type cells.

By immunofluorescence, we found that in primary fibroblasts, staining for DCPS in the nucleus was lost in mutant cells relative to control cells (Fig.  2G).

We have conducted an in silico screen for compounds that preferentially inhibit the growth of p53 mutant cells relative to p53 wild-type cells [ 32].

Quantitative PCR performed on dermal keratinocytes detected reduced levels of DCPS transcripts in heterozygous and homozygous mutant cells relative to control cells.

The average density of the detected sectors, representing the concentration of "mutant" cells relative to "normal" cells, should be greater than 0.5 with probability greater than 0.95.

A marked increase in early apoptosis as measured by increased Annexin V+DAPI− cells was observed for double mutant FL cells relative to wild-type littermate control (Fig. 5).

The screen presented here yielded two novel hits that were extensively validated to be selectively lethal when targeted in KRAS mutant tumor cells relative to cells lacking this mutation.

A similar comparison of mutant cell lines relative to PrPC cells shows the following: PrPΔ51 89 cells show a decrease in ferritin iron and ferritin to 7.0, 6.9%, and insignificant change in Tf and TfR levels.

A similar evaluation of mutant cell lines relative to PrPC-cells shows a decrease in LIP to 95, 78 and 67% in PrPΔ51 89, PrPΔ23 89, PrP102L-cells, and an increase to 155% in PrP231stop cells respectively (Fig. 5A).

This screen uncovered three thiosemicarbazones which preferentially inhibited p53 mutant cell lines relative to p53 wild-type cells.