Sentence examples for mutant cells provided from inspiring English sources

Q-PCR methods were sensitive to detect ≤1% mutant cells, provided that samples yielded cycle thresholds (Ct) <29, but this condition was met in only 38.5% of diagnostic samples.

Behavior of the mutant cells provides genetic evidence for several roles of ICRAC in T cells.

These inverse patterns of localization of M1 and C3 on WT and mutant cells provide evidence that restriction of antibody penetration does not play a role in either the flow cytometry or IF analysis.

In addition, our heterozygous mutant cells provide a useful model to investigate the effects of BAZ1B hemizgosity and WSTF haploinsufficiency in the absence of the loss of the other 27 genes seen in WBS.

9) The invasion of the actin rings in the dendrites in the ankyrin B mutant cells provides the authors with the opportunity to understand the functional importance of these rings.

However, the number of CFU of mutant SM001 cells in the epithelial cells provided evidence that the hemolysin ShlA was not necessary for intracellular replication, but might play a role in the release from the cells.

This latter phenotype was presumably due to the inability of the mutant cells to provide copper to the cytochrome c oxidase [29].

Although the precise mechanism was not clear, IL-6 was significantly reduced by TUDCA treatment in the mutant cells, thus providing a potential therapeutic approach of BSCL2.

We describe GCLC as a part of redox adaptation in TSC, needed for overgrowth and survival of mutant cells, and provide a potential novel target for SEGA treatment.

This observation and others suggest a model for tumor initiation that is associated with the chronic or frequent (e.g., episodic) loss of normal tissue architecture and wound-like ECM remodeling, which enhances rogue behavior of mutant cells by providing a "cancerized" microenvironment [ 37, 38].

Both of these intrabodies colocalize with H-Ras, K-Ras, and G12V mutants inside the cells, providing new potential tools to monitor and modulate Ras-mediated signaling.