Sentence examples for mutant cells contained from inspiring English sources
Moreover, the plasma membranes of wild-type and age3Δ mutant cells contained similar amounts of Cdr1p, Cdr2p and Mdr1p.
The Northern blot revealed that both clpX and clpP mutant cells contained rot-transcript levels that were slightly reduced compared to wild-type levels.
As shown in Fig. 4A, almost all single mutant cells contained the typical dis-like pre-anaphase nuclei (see Fig. 1A).
In contrast, heparan sulfate produced by the mutant cells contained fewer of these smaller oligosaccharides and more extended structures rich in N-acetylated disaccharides (dp>18) were present.
The results revealed that the plasma membrane of mutant cells contained similar amounts of Cdr1p and Cdr2p and possibly a somewhat lower Mdr1p amount compared to the membranes isolated from wild-type and reintegrant cells (Fig. 8B).
The remaining double mutant cells contained two closely situated spots within the same daughter nucleus, suggesting that the sister chromatids had separated but did not move to opposite nuclei.
Thus, vps22, vps25, and vps36 mutant cells contain abnormally large early endosomes that accumulate ubiquitin-conjugated proteins.
In particular, the M2 clones from hMLH1−/− TGFBR2 OF cells revealed that all clones underwent −1 bp frameshift mutation, indicating that the M2 clones are fully mutant cells containing a frameshifted A9/T9 microsatellite.
To examine whether anucleate compartments in cdc16-116 mutant cells contain SPBs, we visualized SPBs using the SPB marker Pcp1p-GFP, a calmodulin-binding protein, which is an essential component of SPB [19], [20].
Clones from M1 populations in hMLH1−/− and hMSH6−/− backgrounds revealed the coexistence of mutated (65±14%, A9 for TGFBR2 and A7 for ACVR2) and WT (35±14%, A10 and A8) microsatellite sequences, indicating the existence of intermediate mutant cells containing A8/T7 or A10/T9 heteroduplexes within the M1 population transferring into full mutant cells as previously observed [25].
Furthermore, the exosomes released from the KRAS mutant cells contain different proteins than non-mutant cells.
