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Most carcinogens are expected to damage the cellular DNA, producing mutant cells (Setlow 1978).
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You can say there is a statistically significant effect for your chemical reducing the firing rate in the mutant cells.
But you can't say mutant and normal cells respond to the chemical differently: to say that, you would have to do a third statistical test, specifically comparing the "difference in differences", the difference between the chemical-induced change in firing rate for the normal cells against the chemical-induced change in the mutant cells.
In that respect, SoBig's variants have acted more like mutant cells in a cancer than a virus, computer security experts say.
Cancer is caused by the unregulated division of mutant cells, which can invade adjacent tissue or travel through the body in a process called metastasis.
He finally secured funding and selected a novel genetic approach: he would chemically induce genetic mutations in yeast cells, then isolate those mutant cells that had malfunctions in the transport and secretory system.
The operation can never remove all breast tissue, and there was always the possibility that enough mutant cells would evade the scalpel to give rise to tumors later on.
(C) Silencing at HMR locus is reduced more dramatically in cells deficient in spt16-m cac1Δrtt106Δ triple mutant cells than in cac1Δrtt106Δ double mutant cells.
It was shown microscopically that mutant cells are smaller, than wild type cells.
(D) Silencing at HMR locus is reduced more dramatically in spt16-m sir1Δ double mutant cells than either of the spt16-m or sir1Δ single mutant cells.
The expression level of A1 in spt16-m sir1Δ double mutant cells is dramatically higher than that in either spt16-m or sir1Δ single mutant cells.
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