Sentence examples for mutant carrier from inspiring English sources

However, injection of either wnt-5 MO resulted in about 50% of embryos with scattered insulin expression in embryos obtained from the wnt-5 mutant carrier outcross.

2 ng of either wnt-5 translation-blocking or exon-intron junction targeting morpholinos were injected into either wild-type embryos or embryos generated from an outcross of a wnt-5 mutant carrier adult.

Mutant carrier G0 animals are outcrossed to wild-type worms of inbred lines to remove possible nonspecific mutations in the genome, which might occur as a result of nonspecific TALEN cleavage.

On the other hand, MDM2-SNP309 was reported to be associated with early onset of breast and ovarian cancer among BRCA1/2 mutant carrier of Jewish-Ashkenazi descent [ 5].

In this study, the expression profiles of breast fibroblast samples from nine heterozygous BRCA1 mutant carrier individuals were compared to the profiles of five reduction mammoplasty fibroblast samples with a very low probability of the presence of BRCA1 mutations as controls.

Extensive sampling of metastatic sites at autopsy revealed 10 distinct PTEN alterations emerging under the selective pressure of PI(3 Kα inhibition [ 3], and five independent reversion events in a germline BRCA2 mutant carrier who progressed on olaparib and carboplatin [ 4].

These studies demonstrated that: (1) All mutant carriers were inserted into the plasma membrane.

Here, single-cysteine mutant carriers were engineered for every residue in the amino- and carboxy-terminus, cytoplasmic loops, and matrix α-helices and their transport activity was measured in the presence and absence of sulfhydryl reagents.

Mutant carriers were in-crossed and progeny raised to 4 dpf.

All analyses were performed using a dominant genetic model, due to the low frequency of homocygote mutant carriers.

However, the length of the segment shared between mutant carriers suggest that the mutation may be older than what has been predicted.