Sentence examples for mutant cannot interact from inspiring English sources

This result correlates with the finding that ErbB1 ΔNLS mutant cannot interact with nucleolin.

Since the A5 mutant cannot interact via the α1, α3 region, this suggests that polymerization of MglB dimers via α1, α3 is not essential for MglB function.

(A ) VASP EVH1 and FL VASP mutants cannot interact with actin filaments in vitro.

Consistent with this notion, the Saw1-ΔRBD mutant that cannot interact with Rad1 showed stronger interaction with Slx4 than its wild-type counterpart.

Using an SXIP defective mutant that cannot interact with EB, we uncover two distinct pools of SKAP at spindle microtubules and kinetochores.

Interestingly, we noticed that mitochondrial degradation was impaired in p62 −/− MEFs complemented with the p62 W340A mutant, which cannot interact with LC3 (Fig. 7B).

Furthermore, the BazS980E mutant, which cannot interact with aPKC, can rescue the function of Baz in both the follicle cells and embryonic epithelia.

To confirm that the interaction is independent of NICD, we repeated the immunoprecipitations in the presence of DAPT to inhibit γ-secretase function and therefore NICD translocation to the nucleus (Fig. 3C, part iii; Fig. 5C), and with the VP16-RBPJκ-K275M mutant that cannot interact with NICD (supplementary material Fig. S7).

Consistent with this notion, expression of unphosphorylatable Ssk1 mutants such as Ssk1-D544S or Ssk1 mutants that cannot interact with Ypd1 (and thus cannot accept phosphate from Ypd1∼P), such as Ssk1-I514T, hyperactheate tHog1og1 MAPK cascade (Horie et al. 2008).

The α1 helix of the Ssk1 REC domain was identified as the interaction site with Ypd1 by isolation of Ssk1 mutants that cannot interact with Ypd1 (Horie et al. 2008).

During infection with ICP27 mutants that cannot interact with RNAP II, viral transcription-replication compartments were poorly formed and Hsc70 focus formation was substantially delayed.