Sentence examples for mutant can rescue from inspiring English sources
Mutations in MA and the gp41 cytoplasmic tail can block Env incorporation, and an MA mutant can rescue an Env-incorporation-deficient Env mutant46.
To validate our hypothesis, we re-expressed wild type or the catalytically inactive mutant PARP1 (E988A) in PARP1-deficient cells, and found that only wild type but not the PARP1E988A mutant can rescue the recruitment of PARP2 (Fig. 4e), suggesting that the catalytic activity of PARP1 is required for the recruitment of PARP2.
Open image in new window Figure 1 The memory formation of svr 1021 mutant is impaired and acute expression of svr + transgene in the svr 1021 mutant can rescue the impairment.
Depending on the cellular context, a kinase-dead IRAK1 mutant can rescue the loss of NF- κB activation observed in IRAK1-deficient cells.
However, previous reports have indicated that an activated MEK mutant can rescue early survival of metatastic osteosarcoma cells expressing ezrin antisense [ 14].
We demonstrate that PINK1 interacts with PARL and that re-expression of wt PARL, but not the catalytically inactive PARL mutant, can rescue abnormal PINK1 cleavage in PARL-deficient cells.
We also attempted a series of experiments to determine whether dimerization deficient mutants can rescue knockdown of endogenous Arf1.
Not surprisingly, neither of these mutants can rescue the clustering defects of Nav or Nfasc caused by the knockdown of endogenous AnkG.
That being said, enhanced Rab5c activity in slb/wnt11 mutant embryos can rescue the mutant phenotype, probably via stabilization of E-cadh localization.
It is unlikely that the reduction of transcription causes the disease phenotype, given that only one functional allele of HTT is needed and that mutant HTT can rescue the lethality in null mutants.
Mutant HTT can rescue the lethal effects of knocking out WT HTT [ 4, 44] so the mutant protein may well be exerting functional effects in relation to its normal as well as its pathological function.
