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The results show that 0.01 pmole of EGFR T790M mutant can be readily detected.
The Cas9 D10A mutant can be used with the same gRNA to introduce DNA nicks on the strand complementary to the gRNA30.
A rapidly-acting conditional mutant can be an invaluable tool in assessing the mechanistic role of a particular transcription factor in vivo.
In these schemes, each mutant can be interconverted by light among at least three conformations that are associated with the protonation-state of the chromophore.
This mutant can be effectively produced as an Aga2p-fusion and purified in soluble form directly from the yeast cell wall.
This mutant can be used as a promising drug candidate for the treatment of psoriasis and may be a therapeutic agent for various other autoimmune diseases.
We showed that one of the mutants can be used to detect glucose from 0 to 32 mM, while another mutant can be employed to visualize intracellular glucose (0 200 μM) within living cells through FRET imaging microscopy measurement.
We conclude that the NA as antigen is dispensable in the live attenuated influenza virus vaccine and that the NA-lacking mutant can be used as a virus vector.
We have produced 99 molecular bar-coded Escherichia coli gene-deletion mutants specific to DNA repair and damage signaling pathways, and each bar-coded mutant can be tracked in pooled format using bar-code specific microarrays.
A single-stranded DNA and its point mutant can be separated with affinity capillary electrophoresis (ACE) in which an appropriate ligand DNA is used as a pseudo-stationary affinity phase.
(D) P62 and its LIR mutant can be degraded in p62 −/− MEF cells.
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