Sentence examples for mutant bound to from inspiring English sources

Here, we present the X-ray crystal structures of a dominant-negative form of human Scp1 (D96N mutant) bound to mono- and diphosphorylated peptides encompassing the CTD heptad repeat (Y1S2P3T4S5P6S7).

The N-terminal deletion mutant bound to ActRIIB in the co-immunoprecipitation assay, which increased with the addition of betaglycan (Figs. 4B and S8).

As shown in Figure 4D, Pc2 and the SIM1 deletion mutant bound to GST-SUMO1, whereas binding of the SIM2 or double SIM mutant was clearly reduced.

Inactive Rac1 mutant bound to the N-terminus of Abi1 (residues 1-186, Fig. 5B) whereas active Rac1 bound to the C-terminal Abi1 fragment containing exon 10 (residues 303-C-terminus, Fig. 5B).

As shown in Fig. 11B, neither NUP98-HOXA9 nor its N51S mutant bound to the HEY1 promoter, supporting the notion that its transactivation is independent of direct homeodomain-DNA interaction.

Proteins were eluted from the protein A coupled antibody column in a final volume of 40 µl. 10 µg of GST-TTC4 (wild type or mutant) bound to glutathione beads was incubated with 6 µg of HSP90 in 10 mM Tris pH 7.5, 150 mM NaCl, 0.1% triton X100 and protease inhibitors (complete EDTA free, Roche).

According to ITC analysis (Supplementary Table S1 and Figure S5), the six mutants bound to Cc with slightly larger KD values than 14-3-3ε FL WT.

These mutants bound to both FADD and caspase-8, but could not block apoptosis or the formation of death effector filaments.

We have determined the three-dimensional structures of selected mutants bound to the substrate analogue nicotinic acid, using X-ray crystallography.

All pyrin mutants bound to PSTPIP1 and reticularized PSTPIP1 filaments in a manner similar to wildtype pyrin (Figure 6A R).

All three mutants bound to PG like the wild-type, and no significant differences in the binding affinity were observed.