Sentence examples for mutant based on the from inspiring English sources

Serine 156 or Asparagine 185 was replaced with alanine or aspartic acid, respectively, by PCR-based site-directed mutagenesis to produce the S156A or N185D AQP5 mutant based on the AQP5 pconstructonstruct as previously described [13].

We report here a Ser127Ala mutant based on the enzyme glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes.

This result favors an alternative explanation to the low levels of P110 in the T192 mutant based on the genetic structure of the transposon insertion in this strain.

However, defective epithelial differentiation was detected in the mutant based on the expression of keratin markers.

To evaluate the possible consequences of introducing an acidic group at this position, we have modelled the wt CaMKII γ C-1 isoform, its phosphorylated form and the S26D mutant based on the structure of PKA (PDB entry 1ATP).

To examine this, we generated an in silico model of the mutant based on the ubiquitin-bound structure of the wild-type enzyme and subjected it to refinement for generating a model with optimized contacts.

In the forward screen, we selected five highly tolerant and four highly intolerant mutants based on the response of seedlings to 300 ppm Fe.

The tagged ST556 mutants were assembled in 96 sets of 55 mutants based on the sequence identity of the tags.

A series of previously generated mutants, based on the GFP-UNG2 construct [50], [51], were transfected into human 143b cells.

We created three groups of XMRV RNase H mutants based on the structural information on XMRV RNase H.

To investigate this further, we designed three hOGT truncation mutants based on the structural data.