Sentence examples for mutant background suggesting from inspiring English sources

However, in A. thaliana these responses were observed only in nim1/npr1 mutant background, suggesting that the NPR1 protein suppresses the plant responses to Rhizobium.

Furthermore, the effect of D-CblL-mPR over-expression was not suppressed in the heterozygous drkEOA mutant background, suggesting that PR of D-CblL might be a critical binding domain for Drk (Table 1).

The incidence of tumors increased in a p53 mutant background, suggesting that the p53 pathway suppresses EWS-FLI1-driven tumorigenesis.

In contrast, expression of an AXR3::GUS reporter was down-regulated in a pax1-1 mutant background suggesting that in wild-type plants, PAX1 regulates AXR3 transcription positively.

Magnetic-induced calcium responses in AFD were not observed in a tax-4 mutant background, suggesting that this requires Ca2+ entering the TAX-4 cGMP-gated ion channel.

Therefore, because DRONC is inactive in ark mutant background suggesting that the cleaved-Caspase-3 labeling signal is not caused by the unknown DRONC substrate, this analysis demonstrates that the cleaved-Caspase-3 antibody does indeed detect cleaved DCP-1.

Furthermore, the smaller 4-fold effect of the G41V mutation in the D38E mutant background suggests that Gly41 helps to position the general base.

The stronger effect of the phx1 mutation in the Δsck2 mutant background suggests that in the absence of the Tor kinase, Phx1 may contribute more to cell survival than in the absence of protein kinase A. Constitutive activation of the Sty1 MAP kinase pathway of S. pombe has also been reported to extend chronological lifespan [ 6].

We observed a strong reduction of HP1c mRNA in two different woc heteroallelic mutant backgrounds, suggesting that besides being a binding partner for Woc, HP1c is also transcriptionally regulated by Woc (Figure 3B).

Contrastingly, mutant clones for cic showed a decrease in ROS levels in both wild-type and rbf1 120a homozygous mutant backgrounds, suggesting that Cic is required for proper ROS homeostasis (Fig. 5).

However, we did observe a slight increase in germ cell deaths in csp-2 tm2858) csp-2 tm28583077) andmals csp-2 tm3077h csp-2 tm3077imanimals the incomparedn germ cell corpses is easily detected in the ced-6(n2095) and ced-2(n1994) mutant backgrounds, suggesting that loss of csp-2 causes increased germ cell deaths and that CSP-2 inhibits apoptosis in germ cells.