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These results confirmed the successful transformation and transcription of the OsNCED4 transgene in the 129B08/nced3 mutant background in two N4C transgenic lines.
Thus we reasoned that we could detect changes in cAMP levels very robustly in a sensitized mutant background in which cpdA was inactivated.
These transgenes were then crossed into a Tsc129 mutant background, in a manner similar to that done by Dong and Pan for Tsc2 [9].
MeJA did also not influence hyponastic growth induced by low light in the phya mutant background (in Ler; Figure 2E), indicating the involvement of PhyA in the interference of JA signaling with this response.
In addition, if the Smn C-T-Neo and/or Smn2B-Neo is used as the Smn mutant background in combination with SMN2 transgenic mice to achieve postnatal survival, new SMA models can potentially be generated with varying degrees of severity.
Moreover, in a mutant background in which auxin transport is severely disrupted (aux1 ein2 gnomeb) exogenous auxin induces root hairs to grow at the end of the cell nearest to the auxin source, even when this is the opposite end from normal [16].
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Although this localization has been described in some mutant backgrounds in S. cerevisiae [23] [29], in wild-type conditions it has been described at the tip of filamentous fungi such as Aspergillus nidulans and Ashbya gossypii [4], [51] as well as at the tip of the germ tube in C. albicans during dimorphic switch [22], [52], [53].
Thus, ΔN-Bcat promotes intestinal polyposis in Apc mutant backgrounds in a synergistic manner, whereas it merely shows additive effects in mutant Kras animals.
Presently, we are in the process of comparing transcriptional changes induced by cic mutations in wild-type and rbf1 mutant backgrounds in order to postulate a molecular mechanism.
None of the Arabidopsis CRF genes show any transcriptional change in response to ethylene or in ethylene mutant backgrounds in microarray experiments.
Robo2's pro-crossing role in the embryo is highlighted in frazzled and Netrin mutant backgrounds, in which midline attraction is partially compromised (Spitzweck et al., 2010).
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