Sentence examples for mutant at this from inspiring English sources

The amino acid side chain of a mutant at this position would point into a hydrophobic niche that also accommodates the side chain of L574 from another monomer.

However, the possibility that Detrick-1 represents a reversion mutant at this locus from Detrick-2 cannot formally be excluded, but since it represented the dominant morphotype in the 1952 Detrick vial we believe this is unlikely.

In fact, E650R is the only mutant at this site that conducts appreciable current with strontium activation.

Although we cannot exclude the possibility that the expression of Runx2 is impaired by E15.5, the gross differences in palatal morphology between wild-type and mutant at this stage are already too large to make a direct comparison.

ChU-B produced by S. cerevisiae retained ~20%and~10%0% of its initial activity at physiological pH with DMP and ABTS as substrates, respectively, whereas the activity of parent type (OB-1 mutant) at this pH was negligible [ 31].

Phosphorylation of the PKA catalytic subunit at T197 has been shown to be essential for the kinase activity, as alanine mutant at this site lowers the catalytic activity by hundreds of fold (Adams et al., 1995; Steichen et al., 2010).

With increasing time, however, there was progressive localization of this mutant at the basolateral surface of the cell.

Masson trichrome staining and hydroxyproline analysis both detected lung fibrosis in this double mutant at the age of 17 months.

The expression of Shh was considerably reduced in the first molar epithelium of Lrp4 and Wise mutants at this stage (Figure 6F, 6H and 7D') suggesting that loss of Shh signaling is linked to the molar fusion process.

An identical expression pattern was observed in PGK Cre Dbx1DTA embryos, although the antero-posterior extent of the various domains appeared reduced compared to wild-types (Fig. 4E H), consistent with the smaller size of mutants at this stage (see Fig. S2A, B).

Another way to test the significance of the T426 site is to co-express the KaiC mutants at this site with KaiCTST in vivo and assess whether the mutant KaiCs affect or disrupt the rhythmicity imparted by the wild-type KaiC.