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Wild type and Δ5 mutant associated with CNX/CRT in a time-dependent manner with a maximal association at the beginning of synthesis.
A defective mutant, associated with the recessive neurodegenerative disease SCAN1, accumulates Tdp1 DNA complexes in vitro.
Here, we examine the self-assembly and promoter-binding energetics of full-length AR and a mutant associated with prostate cancer, T877A.
We found that the percentage of Trak1 hyrt mutant associated with the mitochondrial fraction was significantly decreased compared to that of Trak1 WT or endogenous Trak1 (Fig. 3F H), providing additional evidence for hypertonia mutation-induced impairment in Trak1 mitochondrial localization.
SP therapeutic failures have been associated with presence of the double A437G, K540E mutant associated with the Pfdhfr-ts triple mutant [22], [23].
This is not surprising since SP therapeutic failures have been associated with presence of the "quintuple mutant", namely the Pfdhfr-ts triple mutant associated with the Pfdhps A437G K540E double mutant [22], [23], which was not detected in the village.
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Up to now, many rice mutants associated with chalkiness have been identified and a few genes have been cloned.
In past decade, several rice mutants associated with chalkiness have been identified and a few genes have been cloned.
Advances and areas of uncertainty are discussed on the maize mutants associated with the synthesis of starch in endosperms that have been useful in elucidating the process.
It has recently been observed that many PAH mutants associated with BH4-responsive phenylketonuria display abnormal kinetic and regulatory properties as shown by standard kinetic analyses.
Moreover, ARQ 087 inhibited activity of FGFR1 and FGFR2 mutants associated with Pfeiffer, Apert and Beare-Stevenson craniosynostoses, and rescued FGFR-driven excessive osteogenic differentiation in mouse mesenchymal micromass cultures or in ex vivo calvarial organ cultures.
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