In addition, ral1 mutant is resistant not only to Al but also to Cd.
Interestingly, due to low affinity, the G122H/Y124Q/S125T mutant was resistant to sub-millimolar concentrations of OPs.
These results indicate that Ser214, together with the adjacent dicysteine motif C212/213, are equally essential in mediating the arsenic-PML binding, consistent with the data that S214L mutant is resistant to AS2O3-induced degradation.
We have previously determined that this Casp8RN mutant is resistant to HIV-1 protease cleavage [3].
If a mutation is present in a combination of two drugs, then that mutant is resistant to each drug.
This table indicates if a mutant is resistant to each concentration of each drug; this is marked by a "+".
Plating assays indicated that GlcCer is required for HSAF sensitivity, as the ΔGCS1 mutant is resistant to HSAF (Fig. 6C).
Because the nonmotile δmotAB, δmotCD mutant is resistant to SP-A, the susceptibility to SP-A appears to be independent of flagellar-mediated motility functions.
Conversely, our Glu378 insertion mutant was resistant to aldicarb (Figure 5) consistent with the observed reduction in fusion events in chromaffin cells (Figure 3).
We were surprised that the dna2Δ pif1Δ mutant was resistant to X-rays (Figure 1, the sensitivity of mre11Δ and mre11Δ pif1Δ are shown as controls), since several dna2 hypomorphic mutants are sensitive to IR [31], [36].
