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The triple dilp 2, 3 and 5 deletion mutant and the single dilp6 mutant are both viable, but deletion of all 4 of these dilps is lethal (Gronke et al., 2010), implying functional redundancy between them.

Collectively, our results indicate that the transduction of MPG-EGFP seems to utilize a less well-characterized endocytic pathway [ 23] and suggest that the transduction of MPG-EGFP is dependent on more than singular endocytic pathway, as amiloride and dynamin mutant are both able to reduce the transduction efficiency.

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The MICs of rifampicin and isoniazid to the mutant were both 0.0625 μg mL−1 when 0, 2 and 20 ng mL−1 anhydrotetracycline was added, which were the same to the MICs of rifampicin and isoniazid to wild type strain.

We have observed that the A181P mutant is both functionally defective and unstable, exhibiting increased degradation and association with the Rng3 chaperone.

Indeed, we found that the noncleavable BidD59E mutant was both phosphorylated in mitosis and restored paclitaxel sensitivity to RKO cells following endogenous hBid knockdown.

The pmt3-K14R and pmt3-K14R,K30R mutares are both sensitive to HU (5 mM), while pmt3-K30R is very slightly sensitive to HU.

The Δfsd-1 and Δvib-1 mutants are both defective in female sexual development.

We note that both RasG and RasS mutants are both partially defective in macropinocytosis and yet the Raf1-RBD reporter still localises to nascent macropinosomes in both strains.

These mutants are both unable to influence the nuclear retention of TLE proteins, although they are able to bind to TLE.

Generally, genes down-regulated and up-regulated in rx3 -/- mutants are both enriched in the biological processes " Metabolism", " Regulation" and " Development".

The clv1-11 and crn-1 clv2-1 mutants are both modeled by removing all presence of CLV1 ([CLV1] = [CLV1/CLV3] = 0) and CRN ([CRN] = [CRN/CLV3] = 0) respectively.

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