Sentence examples for mutant and human from inspiring English sources

Wild type, chimera mutant, and human α-subunit deletion mutant ligands were electrophoresed on 4 12% SDS-PAGE gels under non-reducing conditions and transferred to nitrocellulose for immunoblot analysis.

We investigated these questions by using a transgenic mouse model with lymphocyte-targeted expression of p80HT, a lymphoma-associated NF-κB2 mutant, and human multiple myeloma cell lines.

This mouse model harbors the human amyloid precursor protein (APP) gent containing Swedish mutant and human presenilin 1 (PS1) gene encoding the deleted exon 9 mutation under control of mouse PrP promoter which directs the transgene expression predominantly in brain neurons [ 18], and develops amyloid plaques at 6 months of age [ 17].

Adult rabbit and mouse APs were unimpeded on all mutants, and human fH inhibited nonhuman C3 deposition on PorB2-expressing strains, which provided functional evidence for human fH-dependent AP regulation by PorB2.

The strength of the genetic map and genomic resources for this region suggest that comparative DNA sequencing of this region could reveal the genes responsible for other mouse mutants and human genetic diseases.

Evidence suggests conserved mechanisms between Drosophila bang-sensitive mutants and human seizure disorders [ 20].

Significantly, dysfunction of the IGF-1 pathway is a recurrent finding in mouse ataxic mutants and human ataxia patients and thus represents a common neuropathological mechanism that may be targeted for treatment (58).

To verify that the NO-forming activity of eNOS was compromised due to the lack of Ubiad1 and Golgi-CoQ10, we measured NOS activity in bar mutants and human ECs silenced for UBIAD1.

Ctf18 physically associates with Ctf7 in vitro and both ctf18 yeast mutant cells and human cells reduced in Ctf18 levels exhibit cohesion defects [23], [30], [31], [34].

That's where this story begins: a dystopic future, in which Professor X (Patrick Stewart), Magneto (Ian McKellen, Wolverine Hugh Jackmanand and others are hiding out from an attack by robot sentinels that are about to destroy all mutants (and humans).

The film's script is loosely based on two X-Men comic book story arcs: "The Dark Phoenix Saga" by writer Chris Claremont and artist John Byrne, and "Gifted" by writer Joss Whedon and artist John Cassaday, with a plot that revolves around a "mutant cure" that causes serious repercussions among mutants and humans, and on the resurrection of Jean Grey.