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We were able to identify statistically significant metabolic regions that were altered as a result of genetic (gdh1/GD2 mutant) and environmental (excess ammonium and limited potassium) perturbations, and the predicted intracellular metabolic changes were consistent with previously published experimental data including measurements of intracellular metabolite levels and metabolic fluxes.
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In C. elegans, many mutants and environmental treatments confer increased longevity, but the devices by which they do so, or whether or not they are the same, remains unclear.
Use of mutant and environmentally-affected zebrafish showed potential advantages of studying the genetic and environmental factors that modulate the rate of aging in this animal model.
Expression of OsUBC13 can protect a yeast ubc13 null mutant against spontaneous and environmental DNA damage.
Enrichment of these mutants is particularly evident in drug and environmental perturbation screens.
Lastly, in a recent paper, Hu and colleagues [ 43] reported that, in mice with the familial AD-linked mutant APPswe/PS1DeltaE9, environmental enrichment enhanced neurogenesis and was accompanied by a significant reduction in levels of hyperphosphorylated tau and oligomeric Aβ.
Among these mutants, environmental stress-tolerant mutant, and antibiotic-sensitive strains have showed some potential in industrial applications.
The global mechanisms contributing to the attenuation and decreased resistance of the APEC pst mutant to environmental stresses have not been investigated at the transcriptional level.
Swine and environmental isolates from the same data set had 18 (4.75%) and one (0.82%) mutant, respectively, with at least one mutation.
and environmental regulation.
And environmental concerns exist.
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CEO of Professional Science Editing for Scientists @ prosciediting.com