This mechanism is altered in the sunn hypernodulating mutant and consequently auxin continues to be transported from the shoot to the root and sustains supernodulation [ 21].
The signal-to-noise ratio for the Y274W-S96CCPM mutant was significantly lower than for the Y274W-S112CCPM mutand, and consequently, a second P2 phase could not be clearly distinguished, indicating that this FRET pair was not as well suited for measuring conformational changes.
This indicates that these colonies were spontaneous mutants and, consequently, T. maritima was not naturally transformable under the tested conditions.
CT4 overexpression led to the dissociation of SOD1 mutants from Derlin-1, presumably through the competitive interaction with SOD1 mutants, and consequently IRE1, PERK and ASK1 activation was attenuated in the cells.
Importantly, co-expression of Gab1ΔSHP2 in this system blocks the EGF-induced increase in the phosphatase activity of the NS-associated SHP2 mutants and consequently abolishes their positive effect on EGF-induced ERK phosphorylation [ 202].
wox4 pxy mutants were reported with a phenotype stronger than that of pxy single mutants and consequently, an 'enhanced cavity' model was put forward whereby adjacent xylem vessels and phloem were proposed to be the result of differentiation of cells in the vascular meristem, resulting in loss of spatial separation of xylem and phloem (Hirakawa et al., 2010) (supplementary material Fig. S1C).
In our experiment, in the early stage of photoinhibition we do not expect more damage to the mutants and consequently, our result is acceptable showing that the level of singlet oxygen was not significantly more in the PsbS mutant lines compared with wild type.
However, additional deletions to those reported in the published structural characterization of the 39B3 and 39E7 hemizygous deletions [ 20] might occur in the genome of these mutants and consequently we cannot elucidate whether or not a certain down-regulated gene is included in a deleted fragment.
In such a scenario, ICK/KRPs would accumulate in fbl17 mutant pollen and consequently would inhibit the kinase activity mimicking the cdka;1 mutant phenotype.
F values lower than the critical value for a type I error of 0.05 allowed us to accept the null hypothesis, that variance in the mthR3 background was not significantly greater than variance in the mutant background and consequently not responsible for observed differences among lines.
Enhancing the ability of chaperones to assist folding might at least partially rescue trafficking of the mutant proteins, and consequently increase function at the PM.
