Sentence examples for mutant analyses are from inspiring English sources
Further studies using both ribosomal profiling as well as specific mutant analyses are required to advance our understanding of these novel regulatory mechanisms.
These sorts of analyses may also be used much in the same way as mutant analyses are used to identify genes involved in a specific process (i.e., R or S).
These double mutant analyses are consistent with PTRN-1 and TAC-1 acting in a common pathway in regeneration, with EFA-6 acting as a negative regulator of one or both proteins.
Thresholds chosen for WT vs. mutant analyses were 1.5-fold minimum change between WT and KO and difference ≥50, and probe sets in both Picciotto and Xu mutants had to differ from WT in the same direction (i.e., either overexpressed in WT or overexpressed in both mutants).
All the mutants analysed are affected in the hnwd gene involved in the system.
The other mutants analysed are able to bind to pRb but, with the exception of S31G/S32G in raft culture, are unable to induce tetrasomy.
Among these measurements, the data obtained with mutant cycle analyses are more reliable in gauging residue proximities on either side of the toxin-channel interface.
However, given the limitations of having mutations in a single genetic background, new populations of chemically induced mutants for TILLING analyses are currently being developed in other reference strains of several species like rice or soybean [ 22, 23].
Due to the absence of an RpoN deletion mutant, our analyses were restricted to the use of an RpoN over-expressing strain.
Similar Glu homeostasis was observed in many studies on nitrogen nutrition, environmental stress or mutant analyses and was proposed to indicate a special regulatory function of Glu levels [ 44].
Lack of correlation between transcriptional profiling and deletion mutant analyses has been reported in the literature by investigators using both selected individual mutants as well as whole-genome mutant populations [ 53- 57].
