Sentence examples for mutant almost completely from inspiring English sources

R111A mutant almost completely loses the c-di-GMP binding affinity, indicating that R111 is the most important residue for c-di-GMP binding.

Cytoplasmic W241A-TG2 mutalmostmost completely counteracted the effect of serum starvation and increased the viability to ∼95% (Fig. 5).

Interestingly, the sumoylation site lipin-1α-2KR mutalmostmost completely lost its nuclear localization compared to wild-type lipin-1α, although its cytoplasmic localization remained unchanged.

Most remarkably, the R81A/Y87F double mutant almost completely abolished RelE activity.

Moreover, co-expression in HeLa cells of CD4 with Nef R134E followed by FACS analysis showed that this Nef mutant almost completely lost its ability to downregulate CD4.

However, unlike WT, the mice infected with vvpE mutant almost completely maintained their intestinal villi structures, and the inflammation was silenced.

Accordingly, both wild-type recombinant HGSNAT and polymorphic mutants almost completely co-localized with the lysosomal markers LysoTracker Red or LAMP-2 (representative data are shown in Figure 4).

We also demonstrated a transcriptional link between the PTS genes ptsO, ptsM and hprK and the two component system genes bvrR/S establishing a link between virulence and metabolism that was reinforced by the observation that both, ptsP and ptsO mutants, almost completely lost the synthesis of a type IV secretion system (T4SS).

Finally, knockdown of mfn in the background of parkin MUL1 double mutants almost completely rescues the thoracic indentation and mitochondrial phenotypes of parkin MUL1 double mutants.

Furthermore, the double mutant K171,196R, similar to the triple mutant 3KR, almost completely lost the modified bands (Figure 1C, compare lane 5 with 7).

JAK/STAT activation is partly suppressed in the upd2 Δ mutant and almost completely in upd3 Δ and in the double mutant upd2 Δ upd3 Δ (Fig 4E I).