Sentence examples for mutant affects the from inspiring English sources

Thus, the STAT3-YF mutant affects the nuclear translocation of WT-STAT3 in stimulated cells in a concentration-dependent manner.

Interestingly, only the triple-Ala mutant affects the activity; each individual mutation (E134A, E135A, or E138A) has little effect.

To identify whether the Q49X mutant affects the localization of Cx43, we co-expressed Q49X-YFP (or Cx40-YFP) and Cx43-RFP.

This last mutant affects the sumoylation site in p63 and it had been shown that its removal increases the transcriptional activity to 40 50% of TAp63 γ.

Its amino acid substitutions are located in the proximity of the differentially solvent-accessible region 359−370, and this mutant affects the protein allostery driven by AdoMet binding.

However, at present, we cannot give direct evidence that this mutant affects the function, since no insect cell line permitting ClbiNPV infection has been found.

Moreover, neither U2 snRNA mutant affected the 6-AU sensitivity of the double mutant.

To test whether NleLC753A mutant affected the secretion of other type III effectors, we examined the secretion of Tir, a key player in EHEC-mediated actin pedestal formation upon infection.

Finally, we asked whether the R135C mutant affected the activity of the other respiratory complexes.

In the R181L D182L double mutant affecting the same region, two adjacent charged residues are changed to leucines.

Competition with a related dominant negative mutant affected the specific distribution of SYP124 but not tip growth.