The zebrafish genome is sequenced, and genetic mutants affect a wide range of biological processes including development, behaviour, metabolism, vision, immunity and cancer.
In support of this view, most genes down-regulated in triploid peg2 seeds were similarly down-regulated in triploid adm and suvh7 seeds, suggesting that all three mutants affect a common downstream pathway.
This mutant affects open probability to a similar degree as the most effective GOF mutants, I148T/L267P and W275S, is expressed on the surface at similar levels as the other GOF mutants, but responds to the various gating inputs in a manner that is similar to wild type.
(A ) luchs t32241 (luc ) mutant affects Cx39.4 and results in meandering and broken stripes.
It would be interesting to define whether a non-sumoylated H2A.Z mutant affects GAL1 gene anchoring and activation kinetics.
Thus, the STAT3-YF mutant affects the nuclear translocation of WT-STAT3 in stimulated cells in a concentration-dependent manner.
One possibility is that each mutant affects different aspects of SPB duplication.
Moreover, irx14 mutant, affected in a glycosyl transferase involved in cell wall glucuroxylan biosynthesis, has recently been shown to exhibit drought tolerance [41].
