Sentence examples for mutant affecting the from inspiring English sources

In the R181L D182L double mutant affecting the same region, two adjacent charged residues are changed to leucines.

A point mutant affecting the CENP-M/CENP-I interaction hampers kinetochore assembly and chromosome alignment and prevents kinetochore recruitment of the CENP-T/W complex, questioning a role of CENP-T/W as founder of an independent axis of kinetochore assembly.

Every mutant affecting the development of a certain cell type, tissue or organ can be used to better understand not only the physiology of normal development but also the pathological processes underlying congenital malformations, or chronic or degenerative diseases associated with those cells.

Moreover, neither U2 snRNA mutant affected the 6-AU sensitivity of the double mutant.

To test whether NleLC753A mutant affected the secretion of other type III effectors, we examined the secretion of Tir, a key player in EHEC-mediated actin pedestal formation upon infection.

Finally, we asked whether the R135C mutant affected the activity of the other respiratory complexes.

Thus, the STAT3-YF mutant affects the nuclear translocation of WT-STAT3 in stimulated cells in a concentration-dependent manner.

Interestingly, only the triple-Ala mutant affects the activity; each individual mutation (E134A, E135A, or E138A) has little effect.

Competition with a related dominant negative mutant affected the specific distribution of SYP124 but not tip growth.

Its amino acid substitutions are located in the proximity of the differentially solvent-accessible region 359−370, and this mutant affects the protein allostery driven by AdoMet binding.

To identify whether the Q49X mutant affects the localization of Cx43, we co-expressed Q49X-YFP (or Cx40-YFP) and Cx43-RFP.