Sentence examples for mutant affected the from inspiring English sources

Although some data suggested that overexpression of the AS160-4P mutaffectedctexitxit of GLUT4 vesicles from the intracellular storage sites [ 9], other studies proposed that overexpression of the AS160-4P mutaffectedcthe the docking step of GLUT4 translocation in 3T3-L1 adipocytes [ 10, 11].

Moreover, neither U2 snRNA mutant affected the 6-AU sensitivity of the double mutant.

To test whether NleLC753A mutant affected the secretion of other type III effectors, we examined the secretion of Tir, a key player in EHEC-mediated actin pedestal formation upon infection.

Finally, we asked whether the R135C mutant affected the activity of the other respiratory complexes.

Competition with a related dominant negative mutant affected the specific distribution of SYP124 but not tip growth.

Thus, the STAT3-YF mutant affects the nuclear translocation of WT-STAT3 in stimulated cells in a concentration-dependent manner.

In the R181L D182L double mutant affecting the same region, two adjacent charged residues are changed to leucines.

Interestingly, only the triple-Ala mutant affects the activity; each individual mutation (E134A, E135A, or E138A) has little effect.

Its amino acid substitutions are located in the proximity of the differentially solvent-accessible region 359−370, and this mutant affects the protein allostery driven by AdoMet binding.

To identify whether the Q49X mutant affects the localization of Cx43, we co-expressed Q49X-YFP (or Cx40-YFP) and Cx43-RFP.

This last mutant affects the sumoylation site in p63 and it had been shown that its removal increases the transcriptional activity to 40 50% of TAp63 γ.