Sentence examples for mutagenicity tests from inspiring English sources
Our review of these data indicates adequate sensitivity of batteries of in vitro short-term mutagenicity tests in identifying germ cell mutagens.
Nitrite screening of cutting fluids in the field is an interesting method for identifying samples that potentially contain NDELA and other unknown mutagens and, when performed with short-term mutagenicity tests, nitrite screening seems to be a valid tool by which industrial managers and health officers could minimize the health hazards associated with occupational exposure to cutting fluids.
Yang et al. (2008) compiled a group of 2,428 compounds, each of which has structural information and data for six mutagenicity tests, and showed that the percentage of industrial chemicals that were mutagenic was greater than that of chemicals used as drugs or food ingredients.
Typical mutagenicity tests include a bacterial point mutation test (the Ames test), a chromosomal aberrations test in mammalian cells in vitro, and an in vivo (intact animals) test.
The most commonly used regulatory genetic toxicology tests are a series of well-characterized mutagenicity tests, which include in vitro bacterial and mammalian assays, as well as in vivo mammalian assays.
Thus, in short-term mutagenicity tests, the acrylates and methacrylates behave as a single chemical category, and genotoxicity behavior of a similar chemical can be predicted with confidence by inclusion within this chemical class, thus avoiding unnecessary testing.
We see that the data sets for CPDB [19] and Ames Mutagenicity [20] both gives an exact match, and that this compound has previously been shown to be positive (mutagen) in an Ames Mutagenicity test as well as positive for an in vivo carcinogenicity test included in the Carcinogenicity Potency Database.
In a clinical study, changes in 14 biomarkers of exposures (BOEs) from 10 tobacco smoke constituents and mutagens detected by the urine mutagenicity test were investigated using a non-combustion inhaler type of tobacco product (NCIT) by switching from a conventional cigarette.
The purification of cooking mutagens depends on the extraordinary sensitivity of the Ames/Salmonella mutagenicity test and its usefulness for tracking the mutagens during the purification steps.
They are proficiently overviewed in panel reports such as the Food and Drug Administration's Redbook or the OECD Test Guidelines for Genotoxicity and Mutagenicity Testing.
Asbestos fibers without a coating of benzo(a pyrene or benzo(a pyrene when not dissolved in DMSO lacked any mutagenic effect in the Salmonella/mammalian microsome mutagenicity test.
