Sentence examples for mutagenic analysis of from inspiring English sources

Complementary to these studies was a mutagenic analysis of subunit N in E. coli [32].

To first characterize the PER CRY interaction, we performed an alanine-scanning mutagenic analysis of PER2-CBD.

Our mutagenic analysis of the HP1α gene promoter region also revealed a possible role for YY1 in differential expression between MCF7 and HS578T cells.

Here we present a mutagenic analysis of berberine bridge enzyme [BBE, (S -reticuline oxidaS -reticuline.3], which addresses the roxidaseHis174 in flavin rECctivity and bicovalent cofactor linkage.

Previous mutagenic analysis of this residue has shown that while this ionic interaction between oppositely charged residues is not required for ligand binding, it does contribute to ligand affinity [ 37]; however, it is unclear how the specific residue present at this position within a given species affects binding.

Ligand binding is mediated by the CTLD and although the structure of this domain has been solved, and functionally examined by mutagenic analysis, the mechanism of carbohydrate recognition is still unclear.

However, to fully understand the role of protein sectors, the use of mutagenic analysis can provide further information.

Mutagenic analysis and molecular modulation of Pi binding residues are some of the best ways to examine and appreciate the functional role of residues in the catalytic site.

Our mutagenic analysis employed a series of conservative or non-conservative changes, and so was used to assess the binding phenotypes induced by residues present in other FIV isolates (Figure 5A).

A structure-based mutagenic analysis led to a deeper understanding of the role of bicovalent flavinylation for catalysis and to the proposal of a concerted mechanism for BBE.

Our mutagenic analysis showed that disrupting either of these two β-sheets results in either reduced or abolished transport activity (Fig. 2B).