Sentence examples for mutagenesis is increased from inspiring English sources

In addition, in hmo1 mutant cells, spontaneous and damage-induced mutagenesis is increased (Alekseev et al, 2002; Kim & Livingston, 2006, 2009), suggesting a possible role for Hmo1 in DDT or its regulation.

The modifications are as follows: 1: the length of the anchoring homologous sequences of both mutagenesis primers were increased to 16 - 22 bp to achieve melting temperatures greater than 80°C.

Because Msh2 also functions in another heterodimer with Msh3, which recognizes larger IDLs, Msh6-deficiency is in principle best suited to test the idea if the ENU mutagenesis efficiency can be increased in a MMR-deficient background.

We hypothesized that the efficiency of the ENU-driven target-selected mutagenesis approach could potentially be increased in a MMR-deficient genetic background, as this system is involved in the response to and repair of ENU-induced genetic damage [ 17].

Then, the diversity was increased by soft oligonucleotide-directed mutagenesis.

The intracellular concentration of SAM has been increased by a strain improvement based on mutagenesis.

The melting point of CEL7A was increased through a combination of random and site-directed mutagenesis and screening (US 2007/0173431).

The reversion rates in sod1 strains are increased over wild-type strains, but the increase in reversion rates in the absence of MMR demonstrates that in many cases much of the potential mutagenesis due to increased ROS was concealed by the presence of MMR.

Specifically, our data support that lethal mutagenesis occurs in vivo since increased mutagenesis is associated with decreased specific infectivity and fitness of the virus population.

Furthermore, mtDNA mutagenesis is associated with an increase in mitochondrial H2O2, reduced PSC reprogramming efficiency, and self-renewal.

Site-directed mutagenesis, random mutagenesis, and site-saturation mutagenesis were utilized to increase the OP-degrading activity of Dr-OPH.