Sentence examples for mutagenesis in a from inspiring English sources

Insertional mutagenesis in a haploid background can disrupt gene function.

Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy.

Here, we show that HLTF and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV and MMS, respectively.

In Test A, we examine the influence of the antioxidant on induced oxidative mutagenesis in a repair-proficient strain.

To analyze the impact of these RT mutations on viral replication, a double mutant containing K65R + L74V was created by site-directed mutagenesis in a pNL4-3 background.

In this study, the contributions to binding affinity in the CDR2 and CDR3 regions of two monoclonal antibodies E3.3 and 2H2 were investigated by random mutagenesis in a phage-display synthetic oligonucleotide library.

TALENs are used for site-specific mutagenesis in an extended range of organisms including insects.

We combine structure-based drug design with rapid synthetic techniques and mutagenesis, in an iterative fashion, to develop novel antifolates that are not derived from the substrate and cofactor, and to understand the molecular basis for the observed species specificity.

Thus, crossing a Cre driver mouse with a mouse carrying a floxed gene enables conditional mutagenesis in an inducible way.

Secondly, a strict screening strategy on the 8 12 seed region of sgRNA would help decrease undesired mutagenesis in an off-target region.

Gene trapping varies from targeted mutagenesis in that a construct carrying a reporter gene can insert into a gene, disrupting its function.