Sentence examples for mutagenesis experiments for from inspiring English sources

This simulation principle could also be extrapolated to similar mutagenesis experiments for other biological pathways.

These results are consistent with the region of interaction determined by mutagenesis experiments for mouse frataxin and the ISCU-NFS1-ISD11 complex (Schmucker et al., 2011).

Such articles often report the discovered evidence (e.g., mutagenesis experiments) for various hypotheses derived via mining these heterogeneous databases of publicly available data and annotations.

We also show that, compared to ENU, EMS produces a similar or slightly higher fraction of non-synonymous mutations, which is preferred in chemical mutagenesis experiments for mutant screens.

The knowledge of a protein's 3D structure enables a wide spectrum of techniques in molecular biology, ranging from rational design of mutagenesis experiments for the elucidation of a protein's function to drug design.

T4 lysozyme, the archetype for viral-type lysozyme GH24v family, has been extensively studied by mutagenesis experiments mainly for investigations of protein folding and stability mechanisms.

Potential mutagenesis experiments were proposed for understanding the potentiation mechanism of genistein and for providing insightful information for drug design targeting at CFTR.

BASS is a novel 26-nm four-helix bundle, consisting of two anti-parallel coiled-coils at its center, stabilized by alternating hydrophobic and ionic four-helical interfaces, which based on mutagenesis experiments, are critical for tetramerization.

To be sure that the same behavior is also observed for the system studied in this contribution, site-directed mutagenesis experiments were carried out for the enzyme present in P. shermanii.

We see this as a general scheme to generate suggestions for mutagenesis experiments, not only obviously generalizable to other immunoglobulin domains, but to other protein systems as well.

These results demonstrate that SPR may help the selection of target residues for mutagenesis experiments and, thus, focus rational drug design, protein engineering, and functional annotation to the relevant regions of a protein.