Sentence examples for mutagenesis events from inspiring English sources

These limitations can be overcome by using genome editing approaches like TALEN (Transcription activator-like effector nucleases), and/or CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats), allowing the introduction of targeted mutagenesis events.

To evaluate this concept, we developed an in vitro culture model of viral latency, consisting of an integrated lentiviral vector with an easily evaluated reporter system to detect targeted mutagenesis events.

Single mutagenesis events can best be studied with small genomes, such as those of bacteria and of viruses.

Injected G0 animals were crossed to wild-type in multiple batches to generate G1 lines with independent ZFN mutagenesis events.

Mutagenesis events were confirmed by sequencing of F1 adults, and the detection primers are listed in Table S1.

Alu mediated mutagenesis events have been widely reported in the literature and most of the studied cancer genes contain a considerable number of Alu elements in their sequences.

The genetic diseases that have thus far been clearly attributed to LINE-1 activity result from a past insertional mutagenesis event disrupting a gene.

The quinone metabolites of 4-OH-E2 can interact with DNA and, in turn, lead to depurination of DNA a potential mutagenesis event (Cavalieri et al. 2001).

Thus, like SOS mutagenesis, gene transfer events that lead to acquired antibiotic resistance are closely linked to stress.

The large collection of trichome marker mutations (Garcia-Bellido and Dapena 1974) set the wing discs apart as appropriate "tools" to study cellular events, including mutagenesis.

(2002) showed that in the absence of Rad57, the DSB-induced recombination of inverted repeats significantly increases mutagenesis associated with repair events.