Sentence examples for mutagenesis data with from inspiring English sources

The relative binding free energies of the four mutant antibodies obtained from MD FEP calculations compare pretty well with the experimental mutagenesis data with the associated squared correlation coefficient of 0.96.

We have previously shown that this approximation can be used to accurately describe experimental protein mutagenesis data with a simple stability threshold model [ 3].

At the same time, unlike the case of stability mutagenesis for which databases such as ProTherm [ 36] are already available, or reactivity mutagenesis for which some datasets have been assembled [ 5], solubility mutagenesis data with structural information has not been presented in a unified manner previously.

The results are consistent with current site-directed mutagenesis data and with the observed selectivity of TAK779 for CCR5 over CCR1 and CCR2.

Small-angle X-ray scattering and mutagenesis data, together with a B-factor analysis of the crystal structures, support this hypothesis and lead to the suggestion that in at least some cases, the evolution of quaternary enzyme structures might serve to optimise the dynamic properties of the protein subunits.

We used our experimental chemical shift perturbation, transferred-NOESY and mutagenesis data, together with available literature data to create a structural model for the PSIP1-PWWP-nucleosome complex with Haddock version 2.1 [ 33] and CNS 1.3 [ 51, 55].

These mutagenesis data are consistent with a role for Anc1 in error-free PRR.

The mutagenesis data were consistent with the proposed model, but the key to the activation of GTP hydrolysis by SRP and SRα in the dimeric complex is the reciprocal trans interaction between the 3'OH of the GTP ribose and the γ-phosphate of the two nucleotides [ 20, 21].

These results are consistent with mutagenesis data that indicated that the concave patch on the NGN domain interacts with the clamp (Mooney et al, 2009; Hirtreiter et al, 2010).

The structural studies are consistent with mutagenesis data on this enzyme.

The results were validated by comparison with mutagenesis data available in the literature for these two ligands, and subsequently corroborated by the recently described mGlu5 crystal structure.