Sentence examples for mutagenesis at each from inspiring English sources

Saturation mutagenesis at each of the six positions did not result in enhanced thermostability in almost all the cases, confirming the crucial role played by each mutation as revealed through the structural study.

S. pombe diploid deletion mutants were systematically constructed with targeted mutagenesis at each ORF, and haploid deletion strains for non-essential genes were isolated.

We determined the DNA sequences corresponding to amino acid residues 12 130 of the random sequence of fd-RP, and this region was subjected to random mutagenesis at each generation.

We created a substrate library of 19

A genome-wide deletion mutant library was constructed in large scale by PCR-based targeted mutagenesis at each target ORF, on the base of the S. pombe genome sequence information provided by the public website at The Wellcome Trust Sanger Institute http://www.sanger.ac.uk.sanger.ac.uk

The isolated plasmids from this culture constituted the saturation mutagenesis library at each position (I85X, G86X, etc).. Successful incorporation of the degenerate NNS codon was verified by Sanger sequencing of the library.

(A) Mutagenesis at CH3 and hinge region converted anti-EGFR/anti-CD3 DVD-Ig into a Half DVD-Ig molecule.

(F) T7E1 assays assessed mutagenesis at 2 predicted off-target sites; PCR products were used as a control.

Site-directed mutagenesis at the central GEE sites of VC0395_0300 generated mutants, all of which lacked biofilm forming ability.

Saturation mutagenesis at residue 119 revealed variants with half-lives of ∼24 hours at 37 °C.

The transglycosylation efficiency of the ENGase-based glycosynthases has been improved by systematic mutagenesis at the critical residues of various ENGases (Li et al., 2016).