Sentence examples for mutagenesis analysis in from inspiring English sources

Time-simulation analysis is performed to simulate gene expression profile in mutagenesis analysis (in silico mutagenesis), to predict novel gene expression profiles under different activity of cis-acting sites (forward mapping) and to identify specific binding activity when a particular expression profile is given (reverse mapping).

b) Time-simulation analysis is performed to simulate gene expression profile in mutagenesis analysis (in silico mutagenesis), to predict novel gene expression profiles under different activity of cis-acting sites (forward mapping) and to identify specific binding activity when a particular expression profile is given (reverse mapping).

Selected sites that emerged from the phosphopeptide mapping (Ser, Ser, Thr and Ser) were subjected to site-directed mutagenesis analysis in HEK-293 cells, in order to investigate their role in the cAMP-induced phosphorylation and 14-3-3 14-3-3 14-3-3K2.

These results were then filtered by information content of the alignment in the same way as the SWISS-PROT mutagenesis analysis to result in a list of ∼22,000 SNPs.

Mutagenesis analysis coupled with an in vitro caspase cleavage assay confirmed that VELD in the L12 linker domain of GFAP is the major caspase cleavage site.

Deletion-mutant and site-directed mutagenesis analysis implicated specific residues in the CTD, with apoptogenic function recapitulated by a recombinant CTD (H1.2CTD).

Here we have performed a complete in silico mutagenesis analysis to assess the functional essentiality of all possible nonnative point mutants in the entire hMC4R protein (332 residues).

We also performed in silico mutagenesis analysis to characterize the effects of oncogenic mutations on the negative regulators and to observe the cellular outcome (whether there is/is not inflammation).

The transfection strategy will also accommodate a mutagenesis analysis of structure-function relationships in unique gene families.

Interestingly, in our mutagenesis analysis, the APPL1-binding was affected by W74R and Y89R, but not by F57R point mutation in Rab5.

The ADAN database (Encinar et al., 2009) utilizes the FoldX algorithm (Schymkowitz et al., 2005) to perform an assessment of the stability and affinity of peptide domain complexes under in silico mutagenesis analysis.