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These compounds must undergo multiple phosphorylation steps in vivo, converting them into triphosphosphates, in order to inhibit their targeted DNA polymerase.
Normal cells must undergo multiple genetic "hits" before the full neoplastic phenotype of growth, invasion, and metastasis occurs.
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To replenish these cells, neoblasts residing deep in the mesenchyme must produce cells that mobilize, undergo multiple determination steps, cross the basement membrane, intercalate and differentiate into the epidermis.
The overall NO dioxygenase (NOD) reaction can be summarized as 1 2 3 4 To undergo multiple turnovers, the protein must be re-reduced to the O2-binding competent ferrous state (step 4).
Under appropriate culture conditions, undifferentiated embryonic stem (ES) cells can undergo multiple self-renewal cycles without loss of pluripotency suggesting they must be equipped with specific defense mechanisms to ensure sufficient genetic stability during self-renewal expansion.
Like most people, poets rarely undergo multiple metamorphoses in their lives and art over a short period.
SALMs undergo multiple interactions with other proteins.
Bill and Mary Jo White (pictured above) have health insurance -- a serious concern as both parents undergo multiple surgeries.
Ramseur fell into a coma after the shooting and had to undergo multiple surgeries.
IF proteins can undergo multiple posttranslational modifications.
They frequently undergo multiple sinus surgeries before diagnosis.
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