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To accomplish transmission from person to person, the malaria parasite Plasmodium must undergo complex developmental transitions and survive numerous attacks from the mosquito's innate immunity system [ 2, 4].
Protein physicochemical properties must undergo complex changes during evolution, as a response to modifications in the organism environment, the result of the proteins taking up new roles or because of the need to cope with the evolution of molecular interacting partners.
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Therefore, if B220+ DN T cells were derived from SP T cells they must have undergone complex differentiation process that extended beyond simple loss of the coreceptor and upregulation of B220.
It must be pointed out that glutathione S-transferases may also undergo complex epigenetic changes, such as hyper/hypomethylation, depending on the stage of the carcinogenic progression of the prostate cancer.
These cells undergo complex changes in both cell architecture and behavior23.
The heart must undergo a variety of complex pathways, especially in ways to heal from the infarction [ 22– 22].
We speculate that rather than existing as a static complex awaiting recruitment by these transcription factors, core promoter complexes themselves must undergo compositional changes using cell type-specific components such as TAF9B.
The mitotic spindle is a complex structure that must undergo a highly coordinated sequence of steps to faithfully segregate chromosomes to daughter cells.
However, the production of 2G ethanol is more complex, as the lignocellulosic material must undergo pretreatment to break down the structural matrix, and the polymeric sugars must be hydrolysed to fermentable monomers before microbial conversion to ethanol can take place.
Afterripening, also called Dormancy, complex enzymatic and biochemical process that certain plant embryos must undergo before they will germinate.
Men must undergo ritual circumcision.
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