For muscle to function properly throughout the process of E C coupling, the muscle fibers must maintain functional levels of Ca2+ within the SR.
First, we must recognize that proteins have independent behaviours; they carry out specific functions irrespective of the network and they must maintain this function while interacting with other proteins in the network.
Such neural circuits must maintain stable function in the face of many plastic challenges during learning, development and aging.
These data indicate that both proteins are under strong purifying selection and, therefore, they must maintain some function, perhaps related to their original enzymatic activity, and that they are not on the process of becoming pseudogenes or are under strong adaptive selection.
This fat, while crucial to the birds' survival, also presents a challenge in that the bird must maintain normal physiological function with this additional mass.
For NP engineered cells to have a greater chance at acceptance in the clinic, NP engineering methods cannot interfere with cell implant function, must maintain sufficiently strong contrast for longitudinal tracking, and report on implanted cell function.
In vivo strategies based on retaining the vector within the hydrogels must maintain the vector's function until the cells infiltrate the hydrogels [ 22].
The assembly duct wall must maintain its structural integrity and intended function while being exposed to a harsh environment of pressure, temperature and neutron fluence causing elastic and inelastic deflections and swelling.
Because in order to maintain certain function, the functional sites of proteins must maintain a high degree of conservation.
In a manner similar to protein-coding genes, miRNAs must maintain a level of expression for proper function, and impaired expression may result in diseases [7].
