Sentence examples for must be cleaved from inspiring English sources

To produce a mature and active keratinase, the propeptide must be cleaved on the C-terminal via cis or trans.

For instance, is there a critical death substrate or what is the minimal set of proteins that must be cleaved in order to induce the phenotypic hallmarks of apoptosis?

There are two essential requirements for both HEF and HA to catalyze membrane fusion: (i) The precursor proteins HEF0 and HA0, must be cleaved into the subunits HEF1 (Hand and HEF2 (HEF2.

Third, structural studies suggest that the ADAM protease site on the Notch extracellular domain, which must be cleaved to activate the receptor, is exposed by ligand binding [12].

Conceivably the P. dulcis enzyme must be cleaved so that the resulting two subunits can be correctly positioned to form the catalytically competent enzyme.

Caspases are themselves synthesized as zymogens and must be cleaved in order to be activated.

From the specificity of K-12 ligase (Ruan, 2012), mutanolysin must be cleaving a β-DPP-1,7 α-Hep linkage in the current situation.

Did @StephMcMahon just put @RondaRousey through a table?! Of course, wrestling fans could have assumed that someone's body would be used to destroy furniture, given the Chekhov-ian rule that if a table is set up in a wrestling ring for any reason, it must eventually be cleaved by a falling human.

Microtubules are dynamic structures that must elongate, disassemble, and be cleaved into smaller pieces for proper neuronal development and function.

Importantly, IRE1α-KR43 did not cleave an RNA probe containing the spliced XBP1 sequence (XBP1-BSL spliced ) (Fig 2F), demonstrating that, in order to be cleaved by IRE1α, the consensus sequence must be in the correct structural context.

Gasdermin D can be cleaved by caspase-1 126,62,63.