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A greater effect is typically observed in white, predominantly glycolytic muscles, when compared to red, oxidative muscles (e.g. soleus) [5] [9].
Also, a significant change on nerve-evoked tetanus peak force was detected at 40 Hz in AT muscles when compared to controls (Fig. 2b).
In addition, a recently recognized inducer of autophagy, glycogen synthase kinase (GSK) [24], was activated (less phosphorylated) in PGC-1α converted muscles when compared to the KO (Figure 3B).
Yet we found that, with limited exception, both MPred and FR treatments resulted in reduced synthesis of all of the protein fractions in both soleus and plantaris muscles when compared to Control, indicating that both FR and MPred treatments have a global suppression effect on muscle protein synthesis rate.
It leads to relatively higher EMG activity of the ischiocrural muscles when compared to that of the quadriceps [ 8].
Ireland et al [ 18] suggest that individuals with PFPS have weaker hip muscles when compared to matched control groups.
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Also note the heterogeneous attenuation of the muscle when compared to the left medial pterygoid muscle.
MCAT +/+ mice are thought to have increased catalase activity (up to 50 times higher) in heart and skeletal muscle when compared to wild type mice [32].
At all ages examined, only utrophin expression was elevated in mdx and ms-DKO skeletal muscle when compared to wt skeletal muscle (Fig. 7 A and B).
However, MAFbx/atrogin-1 protein content was not changed in compressed muscle when compared to uncompressed muscle in MG132-treated rats.
Similar to Mbnl1 ΔE3/ΔE3/Mbnl3 ΔE2 skeletal muscles, Clc-1 mRNA was significantly enriched in fraction number 7 in HSA LR skeletal muscle when compared to wild type muscle (Fig. 6H).
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