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For this experiment, muscles were injected with either 1 or 5 μg of ESO per injection (10 and 50 μg total) complexed with the NG-PEI2K PEG550 10 NG-PEI2K PEG550 10
Thus, the overall administered dose could vary from 70 U by session if only the facial muscles were injected to 150 U if all muscle groups were injected.
According to the patient pain pattern, additional muscles were injected in some patients, such as procerus, splenius capitis, suboccipitalis and masseter muscles.
If the pain was predominantly located in, or started from the frontotemporal area, or if TrPs were demonstrated in corrugator and temporalis muscles, or if the topography of pain was suggestive of myofascial involvement, both muscles were injected bilaterally.
When the patients had predominant pain in the back of the head, or when their headache pain frequently started and/or ended in the trapezius muscles, both trapezius muscles were injected.
Control TA muscles were injected with PBS.
Similar(36)
The only significant adverse event we observed was local myalgia when the trapezius muscle was injected.
Next the temporal muscle was injected with 60 μl lidocaine and the activity recorded for another 20 min.
The temporalis muscle was injected in one site rather than in four, and the only cervical muscle injected was the trapezius muscle, with a higher dose (40 U versus 15 U).
Muscle regeneration was monitored in mice (8 10 weeks old) after inducing muscle injury by injecting 20 μL of 10 μmol/L CTX (Sigma) in phosphate-buffered saline (PBS) into the mid-belly of the right TA muscle; the left TA muscle was injected with PBS (20 μL) as a control.
The left TA muscle was injected with PBS (same volume) and served as control.
More suggestions(15)
muscles were implanted
muscles were examined
muscles were compared
muscles were spared
muscles were analysed
muscles were mounted
muscles were dissected
muscles were harvested
muscles were stained
muscles were frayed
muscles were stitched
muscles were cramped
muscles were detached
muscles were prepared
muscles were omitted
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